11D/10N Ohio River Cruise


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Cruise Dates: June 28, 2017, July 08, 2017, July 18, 2017

Ohio River Cruise

This incredible journey from St. Louis to Pittsburgh includes enchanting ports including Paducah, Madison, and other beautiful river destinations.

Ports of Call



About Ohio River Cruise

Experience the picturesque waterways of the Mississippi and Ohio Rivers aboard the magnificent Queen of the Mississippi. Step back in time to the grand era of paddlewheels as we explore the heartland of America. While the churn of the paddlewheel blends with the sounds of the river, you’ll rediscover the America of the pioneers, boundless optimism and unlimited possibilities.


Day  1
St. Louis, MO

St. Louis is sure to win you over. Take in the Gateway Arch Riverfront, highlighted by the majestic Gateway Arch, which is the largest man-made monument in the U.S. Enjoy St. Louis’ many world-class, free attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum. End your day by relaxing at the Missouri Botanical Garden, one of the world’s top public gardens.

Day  2
Cape Girardeau, MO

Enjoy the charming features of this historic town that was once a French trading post and lively river port in the late 1800s. Today it boasts Civil War sites and a tranquil setting commemorating the Cherokee Trail of Tears. Marvel at the outdoor murals reflecting the area’s rich heritage and enjoy shore excursions to Cape River Heritage Museum and the Red House Interpretive Center.


Day  3
Paducah, KY

Residing at the confluence of the Tennessee River and the Ohio River, Paducah will have you feeling as if you stepped back in time as you walk the streets of this Chicasaw village site. Discover Paducah’s rich history by exploring the Wall to Wall mural program, a collection of over 50 murals that covers a number of subjects including Native American history, the Civil War and area landmarks such as the old Carnegie Library.


Day  4
Henderson, KY

You won’t miss the presence of notable resident, John James Audubon, whose “Birds of America” paintings are recreated in bronze statues located throughout Henderson. Named after Washington’s home on the Potomac, this bucolic river town is steeped in fascinating lore. A private guide will take you through our famous first president’s historic home and grounds.


Day  5
Day of River Cruising

Sit back and enjoy the gentle sounds of the paddlewheel as it churns through the placid waters of the Ohio River. One of the highlights of this cruise is the chance to watch the ever-changing scenery pass by and experience the river as early explorers did centuries ago.


Day  6
Louisville, KY

Named after King Louis XVI of France, Louisville is best known for the famed Kentucky Derby, the first leg of the Triple Crown of Thoroughbred Racing. When you visit, you’ll also discover why Louisville is often referred to as either the northernmost Southern city or the southernmost Northern city in the United States, with prevalent influences from both Southern and Midwestern culture.


Day  7
Cincinnati, OH

As you disembark in Cincinnati, take some time to visit the numerous National Historic Sites via walking tours through Cincinnati’s oldest neighborhoods filled with eclectic architecture. Visit the William Howard Taft National Historic Museum, the National Underground Railroad Freedom Center and Betts House.


Day  8
Maysville, KY

Maysville, KY is a quaint town on the Ohio River with a rich history. An important stop on the Underground Railroad, Maysville was host to Harriet Beecher Stowe in 1883. Your stop will include gentle country scenery and the native sounds of original bluegrass country music.


Day  9
Day of River Cruising

Grab a good book and curl up in one of our spacious lounges as the Queen of the Mississippi makes its way down the Ohio River. Bird watchers and nature enthusiasts will find the Queen of the Mississippi’s top deck to be the ideal location to identify different species of birds and other wildlife that call the Ohio River home.


Day  10
Marietta, OH

The second-largest city in the Parkersburg-Marietta-Vienna West Virginia-Ohio metropolitan area, Marietta was named in honor of Marie Antionette. The town saw booming times during the 18th and 19th centuries as its location on the Ohio River made it an attractive stop for commercial steamboats and travelers.


Day  11
Pittsburgh, PA

End your journey in the “steel city”, Pittsburgh, PA. Long known for it steel manufacturing, Pittsburgh was an essential stop along the Ohio River for national and international commerce becoming a wealthy town in the 18th and 19th centuries.


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